A guide to plasma membrane solute carrier proteins
نویسندگان
چکیده
منابع مشابه
Solute Transport Plant Plasma Membrane
The plasma membrane proton pump (H+-ATPase) energizes solute uptake by secondary transporters. Wild-type Arabidopsis plasma membrane H+-ATPase (AHA2) and truncated H+-ATPases lacking 38, 51, 61, 66, 77, 92, 96, and 104 C-terminal amino acids were produced in yeast. All AHAS species were correctly targeted to the yeast plasma membrane and, in addition, accumulated in interna1 membranes. Removal ...
متن کاملExpression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity.
Member 4 of human solute carrier family 7 (SLC7A4) exhibits significant sequence homology with the SLC7 subfamily of human cationic amino acid transporters (hCATs) [Sperandeo, Borsani, Incerti, Zollo, Rossi, Zuffardi, Castaldo, Taglialatela, Andria and Sebastio (1998) Genomics 49, 230-236]. It is therefore often referred to as hCAT-4 even though no convincing transport activity has been shown f...
متن کاملJuvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.
PURPOSE SLC16A12 encodes an orphan member of the monocarboxylate transporter family, MCT12. A nonsense mutation in SLC16A12 (c.643C>T; p.Q215X) causes juvenile cataract with a dominant inheritance pattern. In the present study, in vitro and in vivo experimental models were used to gain insight into how the SLC16A12 (c.643C>T) mutation leads to cataract formation. METHODS MCT12 peptide antibod...
متن کاملCharacterization of solute carrier SLC38A6
Transport across the membrane of a cell is of crucial importance for cellular functions. The solute carrier family, SLC38 is a family of membrane proteins that transports various substances through the membrane and thus performs many physiologically important functions, for example, transport of glutamine from astrocyte to neurons in the central nervous system. In this paper, we demonstrate tha...
متن کاملA guide to membrane computing
Membrane systems are models of computation which are inspired by some basic features of biological membranes. In a membrane system multisets of objects are placed in the compartments de.ned by the membrane structure, and the objects evolve by means of “reaction rules” also associated with the compartments, and applied in a maximally parallel, nondeterministic manner. The objects can pass throug...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2020
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.15531